Mitral Valve Stenosis Explained Clearly – Pathophysiology, Symptoms, Treatment

okay well to another MedCram lecture
we’re going to talk about mitral stenosis we’re talking about the
features the symptoms the physical diagnosis the diagnosis treatment and
when to do surgery on mitral stenosis so almost all mitral stenosis is related
to rheumatic heart disease remember what rheumatic heart disease is you have an
infection and then you have these antibodies that are floating around that
would like to attack bacteria but instead they attack your valves and
specifically we’re talking about this mitral valve here typically this occurs
twenty years after rheumatic heart disease and we usually see romatic heart
disease in there we’ll countries for some reason in the tropics it tends to
occur more quickly it’s sped up than it does in the more northern latitudes
we’re not exactly sure why that might be but think about this in 30-year old
patients it may be younger if you’re talking about in the more tropical areas
of the world you’re gonna see this in the 30 year old
patients because 20 years ago when they were 10 they may have had rheumatic
heart disease or some sort of a and infection at that time so the symptoms
are pretty straightforward basically you’re gonna see dis Mia which is
shortness of breath you’re gonna see orthopnea which is shortness of breath
when you lay down and you might see something called paroxysmal nocturnal
dyspnea where they basically they wake up and they’re all of a sudden short of
breath sometimes you might actually see hemoptysis this is because there’s so
much back pressure in the left atrium going back to the lungs that the small
capillaries in the lungs actually rupture and you get like pink frothy
sputum type of thing so you might actually see him opt assist with this
but it’s it’s kind of rare II don’t expect to see that because the left
atrium gets so large you might also see atrial fibrillation and that usually
occurs because you’ve got a dilated atria and because it’s so dilated
sometimes you might even see thrombus in there sometimes because this is so
stano’s you might actually get a jet lesion in the left ventricle that can
cause problems sometimes the left atrium can become so large that it will
actually splay the left mainstem bronchus up and cause obstruction and
you can get pneumonia so those are all different possibilities that you can see
in terms of symptoms for mitral stenosis but the big one that you should know
about it’s just shortness of breath shortness
of breath when lying flat shortness of breath when laying flat at night and
waking up short of breath going to the window type of thing I guess if you were
to have a thrombus here it got kicked off it would go out into the systemic
circulation and you could go up and get strokes so a CVA okay so in terms of
physical diagnosis you’re going to notice that the s1 is going to be louder
and that’s because of the stenosis of the mitral valve remember when the when
you have systolic section of the left ventricle you’re
gonna have objection of blood it’s gonna close this if it is relatively stenosis
it’s going to cause a louder s1 the other thing you’ll notice is remember
the opening snap the opening snap occurs at the beginning of diastole when the
the mitral valve opens the one thing I should say about the opening snap is
that it occurs right after s2 so you have this thing called s2 / OS and
remember s2 marks the end of systole and the beginning of diastole the key here
is that if the opening snap occurs earlier and there used to be trained
physicians that could actually measure this into the hundreds of seconds but
suffice to say that if the opening snap is heard earlier that means it’s opening
up early in diastole and that could only mean if it’s opening up earlier that
there must be a bigger gradient across this valve the bigger the gradient the
worst the mitral stenosis so let me review that if you have bad mitral
stenosis the pressure in the left atrium is going to be much higher than that in
the left ventricle and diastole as a result of that the opening sound or the
opening snap is going to occur earlier so earlier equals worse now the murmur
itself is best heard at the apex you may even want to get the patient the left
lateral decubitus position but what you’re going to hear is a low-pitched
rumbling diastolic murmur rumbling okay this is the same murmur that you
might want to call in Austin Flint if you’re seeing aortic regurgitation
so low-pitched diastolic rumbling murmur what is going to make this larger
anything that increases the amount of blood on the left side of the heart is
going to make this bigger so on exhalation okay that’s going to do it so
an exhalation you have a shift of a septum going to the left the right side
becomes bigger the left side becomes smaller
so exhalation is gonna make the sound larger things that’ll make the sound
smaller would be a valsalva because remember of L Selvam it’s the heart
small on both sides this is the murmur now what else might you hear you might
hear a p2 now what might you hear a p2 because if the pressure in here is built
up it’s gonna back up through the lungs into the pulmonary artery which is going
to make a larger sound than you would normally have so you’re gonna have it
increased p2 and as a result of that you may also see if it’s been there for
awhile right ventricular hypertrophy because you’ll have elevated pulmonary
artery pressures so I think the keys here are that you’re gonna see an
increase s1 you’re gonna hear an opening snap the earlier the opening staff the
more severe the mitral stenosis you’re gonna hear a low pitch rumbling
diastolic murmur and you may hear a p2 due to pulmonary hypertension and
increased by ventricular lift from right ventricular hypertrophy okay let’s talk
about diagnosis on EKGs what you’ll see is enlargement of the RV and the left
atrium and you might see atrial fibrillation so what do you see with an
RV if you look at the precordial leads like v1 v2 v3 you’re going to see that
the QRS complexes are going to be large okay so those think about right
ventricular hypertrophy the QRS complexes are gonna be large in the
precordial leads in terms of left atrium also look at v1 v2 and what you’ll
notice there is you’ll see that there’s a large up component and then down
component before the QRS if it’s more than one small box up and one small box
down in terms of this measurement here on the p-wave that shows that there is a
large left atrial size or of course you could have atrial fibrillation where
there won’t be any pea waves at all and that could be a sign
that you’ve got mitral stenosis not very specific but definitely something to
pick up on what about chest x-ray well if you have your chest x-ray you’ll
notice on the chest x-ray that sometimes you’ll have this double bubble so you’ll
have the heartburn border and then behind it right about here you’ll see
another double density that double density is actually the left atrium I
encourage you to go online and take a look at some x-rays of people with
mitral stenosis so you can see it it’s almost pathognomonic and you might see
it on a test the other thing you might see if the mitral stenosis is fair
enough is you’ll see what we call cephalization so the pulmonary
vasculature is going to be engorged or you might see flat-out pulmonary edema
but the real key to diagnosis is echocardiogram once again and with
echocardiography you’re going to see a large left atrium and you’re gonna see a
mitral valve that does not allow flow to go through and there’ll be a huge
gradient here and that’ll tell you that the Doppler on that echo will tell you
the severity of the stenosis is kind of a way of actually visualizing the
pressure gradient and see the thing that leads to the early opening snap of
course if that is the case the next step is cath because in this situation you
can do surgery or treatment for for this so we’ll talk about that now because the
lungs are filling up with fluid and the patients are usually distich we usually
use loop diuretics like lasix the other thing to do is if you’ve got a trio
fibrillation need to treat that and so anticoagulants like coumadin and rate
control you want to keep the rate down unlike in arrogance efficiency and
certainly if there are clots here you don’t want those clots to go through and
embolize up to the brain so anticoagulation will be key now
sometimes you can actually do balloon valvuloplasty that’s reaction to the
balloon and open this area up that’s usually effective if there’s no
calcification of the valve where things could break off and go in embolize or
there’s regurgitation if there is regurgitation in addition to stenosis
then you want to go with valve replacement so you can do balloon valvuloplasty or you can just do what we
call a mitral valve replacement and remember this is even more clot
provoking than the aortic valve and the reason is is because across the aortic
valve you have very high flow the mitral valve on the other hand is much bigger
and therefore there’s not as as fast flow it’s very slow flow and so this is
a very clot clot forming it’s very high risk for clot forming so you need
anticoagulation if you do a mitral valve replacement especially if it’s
mechanical sometimes they’ll say even the INR must be between 2.5 to 3.5 and
of course if they stop anticoagulation they have to be bridged which can get a
little dicey sometimes in terms of surgery so that sums up mitral valve
stenosis the features symptoms pathophysiology diagnosis and treatment
thanks for joining us you

68 Replies to “Mitral Valve Stenosis Explained Clearly – Pathophysiology, Symptoms, Treatment

  1. wow, now i have a much better understanding of Mitral Stenosis .I'd  like to thank you for your time; now i'm waiting on Mitral Regurgitation.

  2. also patients with MS must receive long acting penicillin to avoid rheumatic activity and IEC 
    and MVR must be done before pulmonary HTN becomes irreversible since the treatment in that case will be heart lung transplantation 

  3. Thank you for the video.
    It's basically a simplified and easy to understand the concept for quick revision 🙂

  4. So nicely explained..I had the experience to see these cases in India..its quite interesting to see the pattern in children and into adulthood. Love the videos! Much love from Canada! <3

  5. Very systematically and easily explained a very technical concept. Please upload videos explaining some neurology concepts also. Thank you very much for the Hard work.

  6. Thank you for the explanation . I well focus on your lectures . They are crystal clear and simple . Is it possible to give an explanation on diagnosis of valvular lesions using cardiac catheterisation
    Kind regards

  7. these videos are wonderful and are taking me back to my grad school days! a much needed review as I switch my NP practice from neurology to cardiology!

  8. Terrific explanation! Always worth a good review. I will be taking step 3 in the near future and your clear, concise review makes it enjoyable. Suscribed and will definitely tune in

  9. Hello Dr. thank you for your videos. This video was made in 2013, and I have just reviewed, so late 🙁
    I found myself confused when you said. what makes this larger?, any condition that increases the amount of blood in the L side. then you cited exhalation, because it displaces the ventricular septum toward the LV. The R side becomes bigger and the L side becomes smaller. Hence, the L side is smaller it does not increases the amount of blood in the L side. On the other hand, inhalation is the one that increases the volume on the R side and shift the septum toward the L side, also reduces the VR from the lung veins decreasing the L side of the heart decreasing the murmur intensity. I think exhalation makes the L side bigger but not because of interventricular septum shift toward the L side. I am still confused can you help with that???

  10. Excellent and simple explanation! I have got my final exams in a week and your video was extremely useful!! Highly recommended!! THANK YOU!!!

  11. I have Mitral Valve Stenosis. I had Rheumatic Fever when I was a baby. I've lived with Mitral Valve Prolapse since I can remember. It went from Prolapse to regurgitation to Stenosis. So far they said I don't have to worry about it. But my doctors are keeping a close eye on me.

  12. Thanks for the video! One point about opening snap: is it the higher gradient from LA flowing to LV causing the earlier opening snap?

  13. So helpful. But could you open the topic a little bit more? Like symps, findings, and some spesific infos like If I talk about MS “when do we say it’s serious stenosis —> when mitral valve area <1.5 cm2” or “surgery indix.”
    Other than that u re fantastic, thx a lot !!

  14. Thank you- This was thorough & helpful for me as an echocardiographer to understand MS more thoroughly

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